This series takes place at the Gokuldham Co-operative Housing Society, an apartment complex in Powder Gali, Goregaon East, Mumbai around Gada Family which consists of a successful businessman Jethalal Champaklal Gada, his father Champaklal Jayantilal Gada, his wife Daya and their naughty son Tipendra "Tapu" Gada who is the leader of his friend circle called "Tapu Sena."
Jethalal calls his father Champaklal to keep an eye on Tapu but the opposite happens and he joins hands with Tapu. Most of the episodes are based on Jethalal being stuck in a problem and Taarak Mehta, his best friend, helps him out of it whom Jethalal calls "Fire Brigade."
The show covers topical issues which are socially relevant. The residents of Gokuldham faces daily life problems and finds solutions for it but with a moral value too in a hilarious manner. Although Gokuldham Society consists of 17 flats but the show mostly focuses on the lives of the families, that are of; Jethalal Champaklal Gada, a Gujarati; Taarak Mehta, who is a Gujarati writer; Aatmaram Tukaram Bhide, who belongs to Marathi culture; Dr. Hansraj Hathi, a Bihari overweight doctor; Krishnan Iyer, a scientist from Chennai but has a Bengali wife; Roshan Singh Sodhi, a Punjabi but has a Parsi wife and Patrakaar Popatlal Panday, a bachelor journalist from Bhopal. They always help each-other in their problems, to promote Unity in Diversity.